RESUMO
The vast majority of malignant melanomas in the small intestine are metastasis of cutaneous tumors. Few cases have been published on primary melanomas in this location, some authors consider that they are always metastatic and that the primary tumor has regressed. In this letter, we present the case of a 77-year-old woman with a history of cutaneous melanoma excision 38 years ago who was diagnosed with ileal melanoma in the absence of other lesions during the study of iron deficiency anemia, and we discuss about the origin of this type of neoplasms.
Assuntos
Melanoma , Neoplasias Cutâneas , Feminino , Humanos , Idoso , Melanoma/cirurgia , Melanoma/patologia , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/patologia , Intestino Delgado/patologia , Íleo/patologiaRESUMO
UNLABELLED: Pancreatic carcinoid tumours are extremely infrequent. Usually, the biological behaviour is indolent and diagnosis is late and often casual. We present the case of a patient initially diagnosed as having liver metastasis of unknown origin. PET identified a primary pancreatic site and the initial histologic diagnosis was adenocarcinoma. Following an uncertain response to chemo- and radio-therapy the repeat histologic assessment indicated a carcinoid tumour of the pancreas. After complete surgical resection and liver transplantation, patient remains free of disease. CONCLUSIONS: The co-existence of several diseases with similar morpho-structural features makes diagnosis complicated. PET is of uncertain use in the evaluation of carcinoid tumours, and is considered inferior to 111Indium-octreotide scan. The only curative treatment is surgical resection, with liver transplantation as a valid option in the treatment of these tumours.
Assuntos
Tumor Carcinoide/diagnóstico , Erros de Diagnóstico , Neoplasias Pancreáticas/diagnóstico , Adenocarcinoma/diagnóstico , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Tumor Carcinoide/diagnóstico por imagem , Tumor Carcinoide/tratamento farmacológico , Tumor Carcinoide/radioterapia , Tumor Carcinoide/secundário , Tumor Carcinoide/cirurgia , Cisplatino/administração & dosagem , Terapia Combinada , Desoxicitidina/administração & dosagem , Desoxicitidina/análogos & derivados , Humanos , Neoplasias Hepáticas/diagnóstico , Neoplasias Hepáticas/secundário , Neoplasias Hepáticas/cirurgia , Transplante de Fígado , Masculino , Pancreatectomia , Neoplasias Pancreáticas/diagnóstico por imagem , Neoplasias Pancreáticas/tratamento farmacológico , Neoplasias Pancreáticas/radioterapia , Neoplasias Pancreáticas/cirurgia , Tomografia por Emissão de Pósitrons , Indução de Remissão , GencitabinaRESUMO
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Pancreatic carcinoid tumours are extremelyinfrequent. Usually, the biological behaviour isindolent and diagnosis is late and often casual. Wepresent the case of a patient initially diagnosed ashaving liver metastasis of unknown origin. PETidentified a primary pancreatic site and the initialhistologic diagnosis was adenocarcinoma.Following an uncertain response to chemo- andradio-therapy the repeat histologic assessmentindicated a carcinoid tumour of the pancreas. Aftercomplete surgical resection and livertransplantation, patient remains free of disease.Conclusions: The co-existence of several diseaseswith similar morpho-structural features makesdiagnosis complicated. PET is of uncertain use inthe evaluation of carcinoid tumours, and isconsidered inferior to 111Indium-octreotide scan.The only curative treatment is surgical resection,with liver transplantation as a valid option in thetreatment of these tumours
Assuntos
Masculino , Adulto , Humanos , Tumor Carcinoide/patologia , Neoplasias Pancreáticas/patologia , Neoplasias Hepáticas/secundário , Metástase Neoplásica/patologiaRESUMO
In 10%-15% of patients, myasthenia gravis is associated with thymoma. Because of its site, this tumour can have an un-noticed clinical history over a considerable time and be diagnosed when adjacent structures such as mediastinal vessels, heart or trachea become infiltrated. We present a patient with thymoma and infiltration of the superior vena cava, and which represents an incipient vena cava syndrome. The surgical treatment consisted of complete resection of the tumour including partial replacement of the vena cava with a pericardial patch. The surgery was complemented with radiotherapy.
Assuntos
Timoma/cirurgia , Neoplasias do Timo/cirurgia , Neoplasias Vasculares/cirurgia , Veia Cava Superior , Idoso , Humanos , Masculino , Invasividade Neoplásica , Procedimentos Cirúrgicos Operatórios/métodos , Timoma/patologia , Neoplasias do Timo/patologia , Neoplasias Vasculares/patologiaRESUMO
No disponible
In 10%-15% of patients, myasthenia gravis is associated with thymoma. Because of its site, this tumour can have an un-noticed clinical history over a considerable time and be diagnosed when adjacent structures such as mediastinal vessels, heart or trachea become infiltrated. We present a patient with thymoma and infiltration of the superior vena cava, and which represents an incipient vena cava syndrome. The surgical treatment consisted of complete resection of the tumour including partial replacement of the vena cava with a pericardial patch. The surgery was complemented with radiotherapy
